Increased baseline occupancy of D(2) receptors by dopamine in schizophrenia

The classical dopamine hypothesis of schizophrenia postulates a hyperactivity of dopaminergic transmission at the D(2) receptor. We measured in vivo occupancy of striatal D(2) receptors by dopamine in 18 untreated patients with schizophrenia and 18 matched controls, by comparing D(2) receptor availa...

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Main Authors: Abi-Dargham, Anissa, Rodenhiser, Janine, Printz, David, Zea-Ponce, Yolanda, Gil, Roberto, Kegeles, Lawrence S., Weiss, Richard, Cooper, Thomas B., Mann, J. John, Van Heertum, Ronald L., Gorman, Jack M., Laruelle, Marc
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC16677/
https://ncbi.nlm.nih.gov/pubmed/10884434
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