Increased baseline occupancy of D(2) receptors by dopamine in schizophrenia

The classical dopamine hypothesis of schizophrenia postulates a hyperactivity of dopaminergic transmission at the D(2) receptor. We measured in vivo occupancy of striatal D(2) receptors by dopamine in 18 untreated patients with schizophrenia and 18 matched controls, by comparing D(2) receptor availa...

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Detalles Bibliográficos
Main Authors: Abi-Dargham, Anissa, Rodenhiser, Janine, Printz, David, Zea-Ponce, Yolanda, Gil, Roberto, Kegeles, Lawrence S., Weiss, Richard, Cooper, Thomas B., Mann, J. John, Van Heertum, Ronald L., Gorman, Jack M., Laruelle, Marc
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC16677/
https://ncbi.nlm.nih.gov/pubmed/10884434
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