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Statistical Tests for Detecting Positive Selection by Utilizing High-Frequency Variants

By comparing the low-, intermediate-, and high-frequency parts of the frequency spectrum, we gain information on the evolutionary forces that influence the pattern of polymorphism in population samples. We emphasize the high-frequency variants on which positive selection and negative (background) se...

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Bibliografiske detaljer
Main Authors: Zeng, Kai, Fu, Yun-Xin, Shi, Suhua, Wu, Chung-I
Format: Artigo
Sprog:Inglês
Udgivet: Copyright © 2006 by the Genetics Society of America 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1667063/
https://ncbi.nlm.nih.gov/pubmed/16951063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.061432
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