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Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis

Down-regulation of the cell surface display of class I MHC proteins is an important mechanism of immune evasion by human and animal viruses. Herpesviruses in particular encode a variety of proteins that function to lower MHC I display by several mechanisms. These include binding and retention of MHC...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Coscoy, Laurent, Ganem, Don
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16668/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10859362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.140129797
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