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DNA Binding by Kaposi's Sarcoma-Associated Herpesvirus Lytic Switch Protein Is Necessary for Transcriptional Activation of Two Viral Delayed Early Promoters

Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus-8) establishes latent and lytic infections in both lymphoid and endothelial cells and has been associated with diseases of both cell types. The KSHV open reading frame 50 (ORF50) protein is a transcriptional activato...

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Bibliographic Details
Main Authors: Lukac, David M., Garibyan, Lilit, Kirshner, Jessica R., Palmeri, Diana, Ganem, Don
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114405/
https://ncbi.nlm.nih.gov/pubmed/11435557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.6786-6799.2001
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