Forecasting the antimalarial activities of arylamidinoureas from their measured physicochemical properties.

1 The octanol : water partition coefficient (PC), protein binding coefficients to albumin (Ba) and haemoglobin (Bh), proton magnetic resonance (PMR) chemical shifts and pKa of 8 arylamidinoureas have been measured. 2 There were statistically significant correlations for 7 of the 8 compounds between...

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Hlavní autoři: Gilbert, D, Goodford, P J, Norrington, F E, Weatherley, B C, Williams, S G
Médium: Artigo
Jazyk:Inglês
Vydáno: 1975
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1666716/
https://ncbi.nlm.nih.gov/pubmed/1182339
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