Identification and characterization of a newly recognized population of high-Na(+), low-K(+), low-density sickle and normal red cells

We describe a population of sickle cell anemia red cells (SS RBCs) (≈4%) and a smaller fraction of normal RBCs (<0.03%) that fail to dehydrate when permeabilized to K(+) with either valinomycin or elevated internal Ca(2+). The nonshrinking, valinomycin-resistant (val-res) fractions, first detected b...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bookchin, Robert M., Etzion, Zipora, Sorette, Martin, Mohandas, Narla, Skepper, Jeremy N., Lew, Virgilio L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10859357/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.130198797
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