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Effects on cardiac muscle of the β-adrenoceptor blocking drugs INPEA and LB46 in relation to their local anaesthetic action on nerve
1. As a local anaesthetic on frog nerve, LB46 had 0·4 times the activity of procaine and 2 times that of INPEA. 2. In reducing the maximum rate of depolarization (MRD) of intracellularly recorded cardiac action potentials, LB46 was 20 times more potent than INPEA. 3. As an antagonist of the chronotr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1971
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665935/ https://ncbi.nlm.nih.gov/pubmed/4400181 |
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