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Blocking effect of McN-A-343 on cardiac slowing produced by vagal stimulation

The effect of McN-A-343 was studied by direct administration into the sinus node artery of dogs vagotomized at the mid-cervical level. McN-A-343 blocked sinus bradycardia caused by electrical stimulation of the right vagus, while bradycardia induced by administration of acetylcholine or nicotine int...

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Bibliographic Details
Main Authors: Chiba, S., Hashimoto, K., Kubota, K., Satoh, S.
Format: Artigo
Language:Inglês
Published: 1971
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665803/
https://ncbi.nlm.nih.gov/pubmed/5157729
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