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Inhibition of Squalene Synthase and Squalene Epoxidase in Tobacco Cells Triggers an Up-Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase

To get some insight into the regulatory mechanisms controlling the sterol branch of the mevalonate pathway, tobacco (Nicotiana tabacum cv Bright Yellow-2) cell suspensions were treated with squalestatin-1 and terbinafine, two specific inhibitors of squalene synthase (SQS) and squalene epoxidase, res...

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Detalhes bibliográficos
Main Authors: Wentzinger, Laurent F., Bach, Thomas J., Hartmann, Marie-Andrée
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Plant Physiologists 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166566/
https://ncbi.nlm.nih.gov/pubmed/12226513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.004655
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