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Increased persistent Na(+) current and its effect on excitability in motoneurones cultured from mutant SOD1 mice
Mutations in the enzyme superoxide dismutase 1 (SOD1) initiate a progressive motoneurone degeneration in amyotrophic lateral sclerosis (ALS). Transgenic mice overexpressing this mutation develop a similar progressive motoneurone degeneration. In spinal motoneurones cultured from presymptomatic mice...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Blackwell Science Inc
2005
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665614/ https://ncbi.nlm.nih.gov/pubmed/15649979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.074138 |
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