Allosteric activation of sodium–calcium exchange by picomolar concentrations of cadmium

Chinese hamster ovary cells expressing the bovine cardiac Na(+)–Ca(2+) exchanger (NCX1.1) accumulated Cd(2+) after a lag period of several tens of seconds. The lag period reflects the progressive allosteric activation of exchange activity by Cd(2+) as it accumulates within the cytosol. The lag perio...

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Bibliografske podrobnosti
Main Authors: Dinh Le, Hoa, Omelchenko, Alexander, Hryshko, Larry V, Uliyanova, Alexandra, Condrescu, Madalina, Reeves, John P
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2005
Teme:
Cell Physiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665565/
https://ncbi.nlm.nih.gov/pubmed/15611030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077743
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