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Cardiac troponin C (TnC) and a site I skeletal TnC mutant alter Ca(2+)versus crossbridge contribution to force in rabbit skeletal fibres

We studied the relative contributions of Ca(2+) binding to troponin C (TnC) and myosin binding to actin in activating thin filaments of rabbit psoas fibres. The ability of Ca(2+) to activate thin filaments was reduced by replacing native TnC with cardiac TnC (cTnC) or a site I-inactive skeletal TnC...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Moreno-Gonzalez, Alicia, Fredlund, Jennifer, Regnier, Michael
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665546/
https://ncbi.nlm.nih.gov/pubmed/15611027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077891
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