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Cardiac troponin C (TnC) and a site I skeletal TnC mutant alter Ca(2+)versus crossbridge contribution to force in rabbit skeletal fibres
We studied the relative contributions of Ca(2+) binding to troponin C (TnC) and myosin binding to actin in activating thin filaments of rabbit psoas fibres. The ability of Ca(2+) to activate thin filaments was reduced by replacing native TnC with cardiac TnC (cTnC) or a site I-inactive skeletal TnC...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665546/ https://ncbi.nlm.nih.gov/pubmed/15611027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.077891 |
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