Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity

Regulatory elements that control tetracycline resistance in Escherichia coli were previously converted into highly specific transcription regulation systems that function in a wide variety of eukaryotic cells. One tetracycline repressor (TetR) mutant gave rise to rtTA, a tetracycline-controlled tran...

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Detaylı Bibliyografya
Asıl Yazarlar: Urlinger, Stefanie, Baron, Udo, Thellmann, Marion, Hasan, Mazahir T., Bujard, Hermann, Hillen, Wolfgang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences 2000
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC16653/
https://ncbi.nlm.nih.gov/pubmed/10859354
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