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Cooperative effect of S4–S5 loops in domains D3 and D4 on fast inactivation of the Na(+) channel
Cytoplasmic S4–S5 loops have been shown to be involved in fast inactivation of voltage-gated ion channels. We studied mutations in these loops and their potential cooperative effects in domains D3 (N1151C, A1152C, I1160C/A) and D4 (F1473C, L1482C/A) of the human skeletal muscle Na(+) channel α-subun...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665345/ https://ncbi.nlm.nih.gov/pubmed/15459238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.065912 |
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