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Modeling of Single Noninactivating Na(+) Channels: Evidence for Two Open and Several Fast Inactivated States
Voltage-gated Na(+) channels play a fundamental role in the excitability of nerve and muscle cells. Defects in fast Na(+) channel inactivation can cause hereditary muscle diseases with hyper- or hypoexcitability of the sarcolemma. To explore the kinetics and gating mechanisms of noninactivating musc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440733/ https://ncbi.nlm.nih.gov/pubmed/16513781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073072 |
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