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Muscle mechano growth factor is preferentially induced by growth hormone in growth hormone-deficient lit/lit mice

Two muscle insulin-like growth factor-I (IGF-I) mRNA splice variants (IGF-IEa and IGF-IEb) have been identified in rodents. IGF-IEb, also called mechano growth factor (MGF) has been found to be upregulated by exercise or muscle damage. Growth hormone (GH) is the principal regulator of IGF-I expressi...

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Библиографические подробности
Главные авторы: Iida, Keiji, Itoh, Emina, Kim, Dong-Sun, del Rincon, Juan P, Coschigano, Karen T, Kopchick, John J, Thorner, Michael O
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665252/
https://ncbi.nlm.nih.gov/pubmed/15308683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.069500
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