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Evidence for Growth Hormone (GH) Autoregulation in Pituitary Somatotrophs in GH Antagonist-Transgenic Mice and GH Receptor-Deficient Mice

Growth hormone (GH) modulates the hypothalamic release of somatostatin and GH-releasing hormone; however, there has been no evidence of GH autoregulation on the pituitary somatotroph. To determine the effects of GH on its own regulation, we examined the pituitaries of giant transgenic mice expressin...

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Autors principals: Asa, Sylvia L., Coschigano, Karen T., Bellush, Linda, Kopchick, John J., Ezzat, Shereen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876832/
https://ncbi.nlm.nih.gov/pubmed/10702416
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