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Palmitate increases L-type Ca(2+) currents and the size of the readily releasable granule pool in mouse pancreatic β-cells
We have investigated the in vitro effects of the saturated free fatty acid palmitate on mouse pancreatic β-cells by a combination of electrophysiological recordings, intracellular Ca(2+) ([Ca(2+)](i)) microfluorimetry and insulin release measurements. Addition of palmitate (1 mm, bound to fatty acid...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1665160/ https://ncbi.nlm.nih.gov/pubmed/15090611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.066258 |
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