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Activation of Na(+) −H(+) exchange and stretch-activated channels underlies the slow inotropic response to stretch in myocytes and muscle from the rat heart

We present the first direct comparison of the major candidates proposed to underlie the slow phase of the force increase seen following myocardial stretch: (i) the Na(+)–H(+) exchanger (NHE) (ii) nitric oxide (NO) and the ryanodine receptor (RyR) and (iii) the stretch-activated channel (SAC) in both...

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Detalles Bibliográficos
Main Authors: Calaghan, Sarah, d White, E
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1665066/
https://ncbi.nlm.nih.gov/pubmed/15235080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.069021
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