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Sequential activation of RhoA and FAK/paxillin leads to ATP release and actin reorganization in human endothelium
We have investigated the cellular mechanisms of mechanical stress-induced immediate responses in human umbilical vein endothelial cells (HUVECs). Hypotonic stress (HTS) induced ATP release, which evoked a Ca(2+) transient, followed by actin reorganization within a few minutes, in HUVECs. Disruption...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1664968/ https://ncbi.nlm.nih.gov/pubmed/15155793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.065334 |
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