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Sequential activation of RhoA and FAK/paxillin leads to ATP release and actin reorganization in human endothelium

We have investigated the cellular mechanisms of mechanical stress-induced immediate responses in human umbilical vein endothelial cells (HUVECs). Hypotonic stress (HTS) induced ATP release, which evoked a Ca(2+) transient, followed by actin reorganization within a few minutes, in HUVECs. Disruption...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hirakawa, Masakazu, Oike, Masahiro, Karashima, Yuji, Ito, Yushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664968/
https://ncbi.nlm.nih.gov/pubmed/15155793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2004.065334
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