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Functional roles of cytoplasmic loops and pore lining transmembrane helices in the voltage-dependent inactivation of HVA calcium channels

Voltage-dependent inactivation of calcium channels is a key mechanism for regulating intracellular calcium levels and neuronal excitability. In sodium and potassium channels, the molecular determinants that govern fast inactivation involve pore block by a cytoplasmic gating particle. As we discuss h...

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Autores principales: Stotz, Stephanie C, Jarvis, Scott E, Zamponi, Gerald W
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664770/
https://ncbi.nlm.nih.gov/pubmed/12815185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.047068
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