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Application of chromosomal substitution techniques in gene-function discovery

A consomic rat strain is one in which an entire chromosome is introgressed into the isogenic background of another inbred strain using marker assisted selection. The development and initial physiologic screening of two inbred consomic rat panels on two genetic backgrounds (44 strains) is well underw...

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Detalhes bibliográficos
Main Authors: Cowley, Allen W, Roman, Richard J, Jacob, Howard J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664739/
https://ncbi.nlm.nih.gov/pubmed/14678490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.052613
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