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Transference of recombinant VE-cadherin cytoplasmic domain alters endothelial junctional integrity and porcine microvascular permeability

VE-cadherin constitutes endothelial adherens junctions through a homophilic binding of its extracellular domain and by the anchoring of its intracellular domain to actin cytoskeleton via catenins. The aim of this study was to determine the functional importance of VE-cadherin–cytoskeleton associatio...

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Bibliografiske detaljer
Main Authors: Guo, Mingzhang, Wu, Mack H, Granger, Harris J, Yuan, Sarah Y
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664736/
https://ncbi.nlm.nih.gov/pubmed/14678493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.051086
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