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Transference of recombinant VE-cadherin cytoplasmic domain alters endothelial junctional integrity and porcine microvascular permeability

VE-cadherin constitutes endothelial adherens junctions through a homophilic binding of its extracellular domain and by the anchoring of its intracellular domain to actin cytoskeleton via catenins. The aim of this study was to determine the functional importance of VE-cadherin–cytoskeleton associatio...

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Autores principales: Guo, Mingzhang, Wu, Mack H, Granger, Harris J, Yuan, Sarah Y
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664736/
https://ncbi.nlm.nih.gov/pubmed/14678493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.051086
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