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An unusual Dicer-like1 protein fuels the RNA interference pathway in Trypanosoma brucei

RNA interference (RNAi) is an evolutionarily conserved gene-silencing pathway that is triggered by double-stranded RNA (dsRNA). Central to this pathway are two ribonucleases: Dicer, a multidomain RNase III family enzyme that initiates RNAi by generating small interfering RNAs (siRNAs), and Argonaute...

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Hlavní autoři: Shi, Huafang, Tschudi, Christian, Ullu, Elisabetta
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664728/
https://ncbi.nlm.nih.gov/pubmed/17053086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.246906
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