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The Virulence Activator AphA Links Quorum Sensing to Pathogenesis and Physiology in Vibrio cholerae by Repressing the Expression of a Penicillin Amidase Gene on the Small Chromosome

Activation of the tcpPH promoter on the Vibrio pathogenicity island by AphA and AphB initiates the Vibrio cholerae virulence cascade and is regulated by quorum sensing through the repressive action of HapR on aphA expression. To further understand how the chromosomally encoded AphA protein activates...

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Bibliografski detalji
Glavni autori: Kovacikova, Gabriela, Lin, Wei, Skorupski, Karen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC166470/
https://ncbi.nlm.nih.gov/pubmed/12897002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.16.4825-4836.2003
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