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The Virulence Activator AphA Links Quorum Sensing to Pathogenesis and Physiology in Vibrio cholerae by Repressing the Expression of a Penicillin Amidase Gene on the Small Chromosome

Activation of the tcpPH promoter on the Vibrio pathogenicity island by AphA and AphB initiates the Vibrio cholerae virulence cascade and is regulated by quorum sensing through the repressive action of HapR on aphA expression. To further understand how the chromosomally encoded AphA protein activates...

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Bibliografiset tiedot
Julkaisussa:J Bacteriol
Päätekijät: Kovacikova, Gabriela, Lin, Wei, Skorupski, Karen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12897002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.16.4825-4836.2003
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