Temperature-Dependent Hypermutational Phenotype in recA Mutants of Thermus thermophilus HB27

The recA gene from Thermus thermophilus HB27 was cloned and engineered to obtain insertion (recA::kat) and deletion (ΔrecA) derivatives. Transcription of recA in this extreme thermophile was induced by mitomycin C, leading to the synthesis of a monocistronic mRNA. This DNA damage-mediated induction...

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Pubblicato in:	J Bacteriol
Autori principali:	Castán, Pablo, Casares, Lorena, Barbé, Jordi, Berenguer, José
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2003
Soggetti:	Genetics and Molecular Biology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166453/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12897010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.16.4901-4907.2003
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