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Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2
A hallmark of highly malignant human gliomas is their infiltration of the brain. We analyzed a large number of primary human glioma biopsies and found high levels of expression of an angiogenic regulator, angiopoietin-2 (Ang2), in the invasive areas, but not in the central regions, of those tumors....
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166411/ https://ncbi.nlm.nih.gov/pubmed/12861074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1533394100 |
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