Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2

A hallmark of highly malignant human gliomas is their infiltration of the brain. We analyzed a large number of primary human glioma biopsies and found high levels of expression of an angiogenic regulator, angiopoietin-2 (Ang2), in the invasive areas, but not in the central regions, of those tumors....

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Detaylı Bibliyografya
Asıl Yazarlar: Hu, Bo, Guo, Ping, Fang, Quan, Tao, Huo-Quan, Wang, Degui, Nagane, Motoo, Su Huang, Hui-Jein, Gunji, Yuji, Nishikawa, Ryo, Alitalo, Kari, Cavenee, Webster K., Cheng, Shi-Yuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC166411/
https://ncbi.nlm.nih.gov/pubmed/12861074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1533394100
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