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p21-Activated Kinase 5 (Pak5) Localizes to Mitochondria and Inhibits Apoptosis by Phosphorylating BAD

Pak5 is the most recently identified and least understood member of the p21-activated kinase (Pak) family. This kinase is known to promote neurite outgrowth in vitro, but its localization, substrates, and effects on cell survival have not been reported. We show here that Pak5 has unique properties t...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Cotteret, Sophie, Jaffer, Zahara M., Beeser, Alexander, Chernoff, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166342/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12897128/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.16.5526-5539.2003
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