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p21-Activated Kinase 5 (Pak5) Localizes to Mitochondria and Inhibits Apoptosis by Phosphorylating BAD

Pak5 is the most recently identified and least understood member of the p21-activated kinase (Pak) family. This kinase is known to promote neurite outgrowth in vitro, but its localization, substrates, and effects on cell survival have not been reported. We show here that Pak5 has unique properties t...

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Hlavní autoři: Cotteret, Sophie, Jaffer, Zahara M., Beeser, Alexander, Chernoff, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC166342/
https://ncbi.nlm.nih.gov/pubmed/12897128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5526-5539.2003
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