Estrogen Receptor-Dependent Proteasomal Degradation of the Glucocorticoid Receptor Is Coupled to an Increase in Mdm2 Protein Expression

Glucocorticoids and estrogens regulate a number of vital physiological processes. We developed a model breast cancer cell line, MCF-7 M, to examine potential mechanisms by which the ligand-bound estrogen receptor (ER) regulates glucocorticoid receptor (GR)-mediated transcription. MCF-7 cells, which...

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Bibliografski detalji

Izdano u:	Mol Cell Biol
Glavni autori:	Kinyamu, H. Karimi, Archer, Trevor K.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 2003
Teme:	Transcriptional Regulation
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166332/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12897156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.16.5867-5881.2003
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