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Phosphorylation of the α Subunit of Eukaryotic Initiation Factor 2 Is Required for Activation of NF-κB in Response to Diverse Cellular Stresses

Nuclear factor κB (NF-κB) serves to coordinate the transcription of genes in response to diverse environmental stresses. In this report we show that phosphorylation of the α subunit of eukaryotic initiation factor 2 (eIF2) is fundamental to the process by which many stress signals activate NF-κB. Ph...

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Udgivet i:Mol Cell Biol
Principais autores: Jiang, Hao-Yuan, Wek, Sheree A., McGrath, Barbara C., Scheuner, Donalyn, Kaufman, Randal J., Cavener, Douglas R., Wek, Ronald C.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166326/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12897138/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.16.5651-5663.2003
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