Stem-Loop IV of Tetrahymena Telomerase RNA Stimulates Processivity in trans

Telomerase is a ribonucleoprotein enzyme responsible for the addition of telomeres onto the ends of chromosomes. Short or dysfunctional telomeres can lead to cell growth arrest, apoptosis, and genomic instability. Telomerase uses its RNA subunit to copy a short template region for telomere synthesis...

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Bibliographic Details
Main Authors: Mason, Douglas X., Goneska, Elizabeth, Greider, Carol W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC166324/
https://ncbi.nlm.nih.gov/pubmed/12897134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5606-5613.2003
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