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Stem-Loop IV of Tetrahymena Telomerase RNA Stimulates Processivity in trans

Telomerase is a ribonucleoprotein enzyme responsible for the addition of telomeres onto the ends of chromosomes. Short or dysfunctional telomeres can lead to cell growth arrest, apoptosis, and genomic instability. Telomerase uses its RNA subunit to copy a short template region for telomere synthesis...

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Autori principali: Mason, Douglas X., Goneska, Elizabeth, Greider, Carol W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC166324/
https://ncbi.nlm.nih.gov/pubmed/12897134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.16.5606-5613.2003
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