P2Y(12) regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries

The critical role for ADP in arterial thrombogenesis was established by the clinical success of P2Y(12) antagonists, currently used at doses that block 40–50% of the P2Y(12) on platelets. This study was designed to determine the role of P2Y(12) in platelet thrombosis and how its complete absence aff...

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Bibliografiske detaljer
Main Authors: André, Patrick, Delaney, Suzanne M., LaRocca, Thomas, Vincent, Diana, DeGuzman, Francis, Jurek, Marzena, Koller, Beverley, Phillips, David R., Conley, Pamela B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166294/
https://ncbi.nlm.nih.gov/pubmed/12897207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317864
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