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P2Y(12) regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries
The critical role for ADP in arterial thrombogenesis was established by the clinical success of P2Y(12) antagonists, currently used at doses that block 40–50% of the P2Y(12) on platelets. This study was designed to determine the role of P2Y(12) in platelet thrombosis and how its complete absence aff...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166294/ https://ncbi.nlm.nih.gov/pubmed/12897207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317864 |
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