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Nef increases the synthesis of and transports cholesterol to lipid rafts and HIV-1 progeny virions
HIV buds from lipid rafts and requires cholesterol for its egress from and entry into cells. Viral accessory protein Nef plays a major role in this process. In this study, it not only increased the biosynthesis of lipid rafts and viral particles with newly synthesized cholesterol, but also enriched...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC166251/ https://ncbi.nlm.nih.gov/pubmed/12824470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1437453100 |
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