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The lethal effects of transplantation of Socs1(-/-) bone marrow cells into irradiated adult syngeneic recipients

Injection of neonatal bone marrow cells from mice lacking the gene encoding suppressor of cytokine signaling 1 (SOCS1) into irradiated syngeneic 129/Sv or C57BL/6 mice led to a decreased survival, more rapidly occurring in 129/Sv than in C57BL/6 mice. Moribund mice did not exhibit the acute or chron...

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Autors principals: Metcalf, Donald, Mifsud, Sandra, Di Rago, Ladina, Alexander, Warren S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC166247/
https://ncbi.nlm.nih.gov/pubmed/12821775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1032925100
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