Regulatory CD8(+) T cells fine-tune the myelin basic protein-reactive T cell receptor Vβ repertoire during experimental autoimmune encephalomyelitis

A significant number of self-reactive T cell clones escape thymic negative selection and are released into the periphery, where some are potentially pathogenic. The clonal expansion of self-reactive T cells is known to be limited during initial antigen encounter by apoptotic or anergic mechanisms, r...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Jiang, H., Curran, S., Ruiz-Vazquez, E., Liang, B., Winchester, R., Chess, L.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2003
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12824465/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1432871100
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