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Regulation of cysteine cathepsin expression by oxidative stress in the retinal pigment epithelium /choroid of the mouse

Cystatin C is the major inhibitor of the cysteine cathepsins. Polymorphisms in the cystatin C gene have recently been associated with the risk of developing Age-related Macular Degeneration (AMD). Oxidative stress is also thought to play a key role in the pathogenesis of AMD. We surveyed the retinal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Alizadeh, Parvaneh, Smit-McBride, Zeljka, Oltjen, Sharon L., Hjelmeland, Leonard M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1661778/
https://ncbi.nlm.nih.gov/pubmed/16684524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2006.03.009
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