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Regulation of cysteine cathepsin expression by oxidative stress in the retinal pigment epithelium /choroid of the mouse
Cystatin C is the major inhibitor of the cysteine cathepsins. Polymorphisms in the cystatin C gene have recently been associated with the risk of developing Age-related Macular Degeneration (AMD). Oxidative stress is also thought to play a key role in the pathogenesis of AMD. We surveyed the retinal...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1661778/ https://ncbi.nlm.nih.gov/pubmed/16684524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2006.03.009 |
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