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Constitutive activity of a UV cone opsin

Vertebrate visual pigment proteins contain a conserved carboxylic acid residue in the third transmembrane helix. In rhodopsin, Glu113 serves as a counterion to the positively charged protonated Schiff base formed by 11-cis retinal attached to Lys296. Activation involves breaking of this ion pair. In...

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Bibliografische gegevens
Hoofdauteur: Kono, Masahiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1661692/
https://ncbi.nlm.nih.gov/pubmed/16368093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2005.12.002
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