The Role of Substantia Nigra Pars Reticulata in Modulating Clonic Seizures is Determined by Testosterone Levels During the Immediate Postnatal Period

GABAergic activation of substantia nigra pars reticulata (SNR) at postnatal day (PN) 15 has sex-specific features on seizure control in vivo and electrophysiological responses in vitro. In males, the GABA(A)-receptor agonist muscimol has proconvulsant effects and induces depolarizing responses. In f...

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Hauptverfasser: Giorgi, Filippo S., Velíšková, Jana, Chudomel, Ondřej, Kyrozis, Andreas, Moshé, Solomon L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1661598/
https://ncbi.nlm.nih.gov/pubmed/17011203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2006.08.009
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