The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice

BACKGROUND: Streptococcus pneumoniae possesses large zinc metalloproteinases on its surface. To analyse the importance in virulence of three of these metalloproteinases, intranasal challenge of MF1 outbred mice was carried out using a range of infecting doses of wild type and knock-out pneumococcal...

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Veröffentlicht in:	BMC Microbiol
Hauptverfasser:	Chiavolini, Damiana, Memmi, Guido, Maggi, Tiziana, Iannelli, Francesco, Pozzi, Gianni, Oggioni, Marco R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2003
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166150/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12841855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2180-3-14
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