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The three extra-cellular zinc metalloproteinases of Streptococcus pneumoniae have a different impact on virulence in mice

BACKGROUND: Streptococcus pneumoniae possesses large zinc metalloproteinases on its surface. To analyse the importance in virulence of three of these metalloproteinases, intranasal challenge of MF1 outbred mice was carried out using a range of infecting doses of wild type and knock-out pneumococcal...

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Bibliografiske detaljer
Main Authors: Chiavolini, Damiana, Memmi, Guido, Maggi, Tiziana, Iannelli, Francesco, Pozzi, Gianni, Oggioni, Marco R
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166150/
https://ncbi.nlm.nih.gov/pubmed/12841855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-3-14
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