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Molecular surveillance of the antifolate-resistant mutation I164L in imported african isolates of Plasmodium falciparum in Europe: sentinel data from TropNetEurop

BACKGROUND: Malaria parasites that carry the DHFR-mutation I164L are not only highly resistant to sulfadoxine-pyrimethamine but also to the new antimalarial drug chlorproguanil-dapsone. The spread of this mutation in Africa would result in a public health disaster since there is a lack of effective...

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Dades bibliogràfiques
Publicat a:Malar J
Autors principals: Wichmann, Ole, Jelinek, Tomas, Peyerl-Hoffmann, Gabriele, Mühlberger, Nikolai, Grobusch, Martin P, Gascon, Joaquim, Matteelli, Alberto, Hatz, Christoph, Laferl, Hermann, Schulze, Marco, Burchard, Gerd, Cunha, Saraiva da, Beran, Jiøi, McWhinney, Paul, Kollaritsch, Herwig, Kern, Peter, Cuadros, Juan, Alifrangis, Michael, Gjørup, Ida
Format: Artigo
Idioma:Inglês
Publicat: BMC 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC166141/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12869209/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1475-2875-2-17
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