Molecular surveillance of the antifolate-resistant mutation I164L in imported african isolates of Plasmodium falciparum in Europe: sentinel data from TropNetEurop

BACKGROUND: Malaria parasites that carry the DHFR-mutation I164L are not only highly resistant to sulfadoxine-pyrimethamine but also to the new antimalarial drug chlorproguanil-dapsone. The spread of this mutation in Africa would result in a public health disaster since there is a lack of effective...

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Bibliographische Detailangaben
Hauptverfasser: Wichmann, Ole, Jelinek, Tomas, Peyerl-Hoffmann, Gabriele, Mühlberger, Nikolai, Grobusch, Martin P, Gascon, Joaquim, Matteelli, Alberto, Hatz, Christoph, Laferl, Hermann, Schulze, Marco, Burchard, Gerd, Cunha, Saraiva da, Beran, Jiøi, McWhinney, Paul, Kollaritsch, Herwig, Kern, Peter, Cuadros, Juan, Alifrangis, Michael, Gjørup, Ida
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2003
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166141/
https://ncbi.nlm.nih.gov/pubmed/12869209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-2-17
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